OVARIAN HIRSUTISM
Ovarian hirsutism can be a consequence of a tumoral or non-tumoral cause.
NON-TUMORAL:
POLYCYSTIC OVARY SYNDROME
OVARIAN HYPERTRICHOSIS
TUMORAL: free testosterone greater than 200 ng/dl
ARRENOBLASTOMA, HILAR CELL TUMOR, GRANULOSA CELLS, BRENNER’S TUMOR, GONADOBLASTOMA
Exploration shows that hirsutism grows more laterally and appears on breasts and in cases of obesity, acne and seborrhoea, amenorrhea. We will now focus on the condition most frequently seen in practices or POLYCYSTIC OVARY SYNDROME.
POLYCYSTIC OVARY SYNDROME
It is one of the most frequent causes of hirsutism in clinical practice.
Classic clinical picture and other recently wide spectrum described forms: Amenorrhea, hirsutism, obesity, chronic anovulation, hyperinsulinism (decreased levels of SBG and increased levels of androgens).
Polycystic ovary syndrome is caused by persistently high LH and low FSH levels, which leads to thecal hyperplasia, increasing androgen synthesis.
INCREASE OF TESTOSTERONE
Androgens and scarce aromatase activity (due to low FSH levels) slow down the maturation of follicles-cysts.